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Newsletter  2016.2  Index

Theme : "The Conference of Fluid Engineering Division"

  1. Preface
  2. Fluids Engineering supporting Artificial Heart
    Takashi YAMANE (Kobe University)
  3. Foam measurement via a single-tip optical fiber probe with surface treatment
    Ayumi NIHEI, Takayuki SAITO (Shizuoka University)
  4. Visualization of a process of ultrasonic particle flocculation depending on dissolved gas components in water
    Sayuri YANAI, Hiroya MURAMATSU, Yuki MIZUSHIMA, Takayuki SAITO (Shizuoka University)
  5. Research for Cerebral Aneurysm Recanalization After Coil Embolization Using CFD
    Soichiro FUJIMURA (Tokyo University of Science)
  6. A Water Bed, Yasutaka
    Naoya UENE (National Institute of Technology, Yonago College)
  7. Music Awa ~Music hour~
    Shuhei HATTORI, Ikuma EMORI (National Institute of Advanced Industrial Science and Technology )


Research for Cerebral Aneurysm Recanalization After Coil Embolization Using CFD

Tokyo University of Science



Subarachnoid hemorrhage is the leading cause of death or severe disability, and cerebral aneurysm is a major cause for the disease because of its rupture. Thus, the patients who have unruptured aneurysms need to be obliterated them by clipping or endovascular treatment.
Coil embolization has been one of the most popular methods to treat an unruptured saccular cerebral aneurysm because of its minimal invasiveness. In this method, thin biocompatible metal wires are inserted into an aneurysm by a catheter and the dome region is filled with this medical devices. Leading a thrombus in the aneurysm with the inserted coils, blood flowing into it is prevented and the risk of the aneurysm rupture will be decreased. However, recurrence of aneurysms after coil embolization remains as a major problem. This phenomenon means a re-inflow of blood into the aneurysm because of coil compaction, which means the coil is literally compacted into the aneurysm physically, or re-growth of the aneurysm. Clinical reports showed that around 10% - 25% aneurysms with coil were recanalized. Unfortunately, the risk assessment protocol for such procedure has not been established yet, and the mechanism has not been understood clearly either.
We characterize the hemodynamics of aneurysms before and after first embolization cases using CFD. In this study, the patient specific models of arteries and embolized coil from three-dimensional digital subtraction angiography (3D-DSA) data are used. We process hemodynamic and morphological parameters, and examined the difference of them between recanalized cases and stable cases statistically to investigate the occurrence mechanism of the aneurysm recanalization. The results indicate that some hemodynamic and morphological parameters may be factors for recanalization. From the result, we may propose the patient-specific indicator, volume embolization ratio (VER), to prevent the prospective recurrence of aneurysms.

Key words



Fig. 1 Saccular Aneurysm

Fig. 2 Illustration and Angiographic images of recanalized aneurysm

Fig. 3 Analysis Flow

Fig. 4 Result of Recanalized Case

Last update: 2.16.2016